The one-hour session, titled "Streamline Targeted LNP Development to Improve Preclinical Translation," focuses on moving past the liver-accumulation hurdle that frequently hampers nucleic acid delivery. Industry experts will evaluate iterative formulation techniques, specifically examining covalent conjugation and post-insertion methods. These strategies aim to achieve precise ligand incorporation without compromising the stability or manufacturing feasibility of the nanoparticles.
Allen Horhota, formerly of Seamless Therapeutics, will moderate the discussion. He will be joined by Nicholas Boylan of Phosphorex, Syed Reza of NOF Corporation, and Michelle Bellerose of Neosome Life Sciences. The panel is designed to provide development teams with a practical framework for navigating the transition from initial formulation to preclinical validation. Interested researchers can register for the session through Xtalks.

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